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While agnathans appear to have reduced their
2019-08-08
While agnathans appear to have reduced their Ednr repertoire to the Ednra gene (that may have been amplified in the Arctic lamprey), gnathostomes in general have been relatively inert to Ednr gene loss. Strikingly, the only Ednr gene that has been lost repeatedly is EdnrB2 (lost in therian mammals,
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The activity of cysteine endopeptidases involved in
2019-08-08
The activity of cysteine endopeptidases involved in the germination of caryopses is generally regulated at two levels: the hormonal induction of synthesis by gibberellins (Drzymała et al., 2008) and a putative regulation of activity by phytocystatines (Kiyosaki et al., 2007, Martinez et al., 2009),
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Results from experiments in model systems have suggested tha
2019-08-08
Results from experiments in model systems have suggested that the DPRs translated from the HRE of C9ORF72 are toxic and play a role in disease pathogenesis (reviewed in Taylor et al. (2016)). Although the DPRs are present in neurons and glia in various regions of the central nervous system (CNS) ear
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Oysters belong to the second largest
2019-08-08
Oysters belong to the second largest animal phylum Mollusca, and they are globally distributed aquaculture animals (Wang et al., 2018). A number of studies have demonstrated that oysters have evolved an integrated and complex innate immune system to recognize and eliminate various invaders. An array
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Use of CDK inhibitors in CLL today There
2019-08-07
Use of CDK inhibitors in CLL today There has been explosive development of novel therapeutics for CLL in the last decade and a massive transformation of practice is underway [75].
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According to our results germination
2019-08-06
According to our results, germination of transgene dgks lines didn’t differ under optimal conditions and 50 mM NaCl, while 100 mM NaCl slightly affected germination rates of dgk mutants.
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Floxuridine Introduction Pain is frequently the first clinic
2019-08-05
Introduction Pain is frequently the first clinical symptom of head and neck carcinoma. Indeed, pain is the initial reason leading ∼70% of cancer patients to seek professional assistance (Lam & Schmidt, 2011; Rettig & D’Souza, 2015; Schmidt, 2014).
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Furthermore down regulation of Cpt a
2019-08-02
Furthermore, down-regulation of Cpt1a, ApoE, Fasn, Pxr, and Srebp-1 genes indicates a down-regulation of lipid metabolism associated genes while Fatp1 is up-regulated and indicates an increase in fatty Tivozanib (AV-951) transport genes involved in accumulation [84,85].
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In addition to EGFR other receptor tyrosine kinases RTKs
2019-08-01
In addition to EGFR, other receptor tyrosine kinases (RTKs) also play roles in the tumor progression under hypoxia, especially hepatocyte growth factor receptor (cMet) (Le et al., 2012).
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As the angular structure of compound
2019-07-31
As the angular structure of compound cannot be differentiated from the linear structure by H NMR spectroscopy, a NOESY NMR experiment was performed to unambiguously characterize the regioselectivity of the final compound.
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Conflict of interest Acknowledgments Dr Hauger was supporte
2019-07-27
Conflict of interest Acknowledgments Dr. Hauger was supported by a BLR&D Merit Review grant from the Department of Veterans Affairs, Veterans Health Administration, Office of Research and Development.
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Interestingly our analyses of human PBMCs using
2019-07-26
Interestingly, our analyses of human PBMCs using a monoclonal antibody against EBI2 showed that the expression pattern of human EBI2 is largely overlapping with that in mice.
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Results and discussion Analysis
2019-07-25
Results and discussion Analysis of experimental data indicates that the radon MEK162 (ARRY-162, ARRY-438162) coefficient in OPC blended with RHA varies from 0.15 × 10−6 m2 s−1 for pure cement to 0.26 × 10−6 m2 s−1 for cement mixed with 50% RHA by weight.
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Social memory is encoded within certain sites
2019-07-24
Social memory is encoded within certain sites, but meaning depends upon an interpretant (such as a tourist) being able to decode the signs.
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A previous study suggested that DARs and octopamine tyramine
2019-07-23
A previous study suggested that DARs and octopamine/tyramine receptors (OARs/TARs) have close pharmacological properties (Beggs et al., 2011).
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